[Early insulin therapy in type 2 diabetes?].
نویسنده
چکیده
Type 2 diabetes is characterized by progressive decline in pancreatic beta cell function and persistent insulin resistance. Decreased beta cell mass and amyloid deposits in the islet are the pathological hallmark of the disease. Preserved beta cell function is the most important determinant of glucose disposal, even after adjustment for insulin sensitivity, which might modulate beta cell function. Besides, beta cell dysfunction is also responsible for several functional abnormalities in type 2 diabetes. These defects include:
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عنوان ژورنال:
- Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
دوره 132 19 شماره
صفحات -
تاریخ انتشار 2012